Related Experiment Videos
X-ray structural characterization of SR 142948, a novel potent synthetic neurotensin receptor antagonist
L Quéré1, G Longfils, R Boigegrain
1Laboratoire de Chimie Moléculaire Structurale, Facultés Universitaires Notre-Dame de la Paix, Namur, Belgium. Luc.Quere@UCB-Group.com
Bioorganic & Medicinal Chemistry Letters
|January 1, 1999
Abstract:
SR 142948 is an original and extremely potent neurotensin receptor antagonist developed in a promising approach to novel antipsychotic drugs. The X-ray structure was elucidated and compared to SR 48692 and levocabastine, providing new informations about the possible recognition process of NT receptor subtypes.