Management of pulmonary complications in neuromuscular disease

The clinician working with patients with neuromuscular disease should be aware of the effects of muscle weakness on the respiratory system. Symptoms may present insidiously and can result in progressive loss of function, respiratory failure, and even death. A number of techniques, including several forms of mechanical ventilation as well as physical aids to assist airway hygiene, are available and are effective in improving symptoms and survival in appropriately selected patients with neuromuscular disease.