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Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome01:23

Irritable Bowel Syndrome

DefinitionIrritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent combinations of abdominal pain, bloating, diarrhea, or constipation.Pathophysiology of irritable bowel syndromeIts pathophysiology is multifactorial, involving disturbances in motility, sensory processing, microbial balance, barrier integrity, and gut–brain communication. These mechanisms interact to produce symptoms that vary across IBS subtypes.Altered Motility PatternsDisordered...

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Related Experiment Video

Updated: Jul 21, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
10:37

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform

Published on: November 30, 2016

Constipation, diarrhea, and irritable bowel syndrome

S M Browning1

  • 1Attending Colon and Rectal Surgeon, Department of Surgery, Wilford Hall Medical Center, San Antonio, Texas, USA.

Primary Care
|March 4, 1999
PubMed
Summary

Common digestive issues like constipation and diarrhea are frequent in primary care. Chronic conditions require evaluation, with dietary changes and fiber effective for constipation, while irritable bowel syndrome is a key diagnosis for chronic diarrhea.

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Area of Science:

  • Gastroenterology
  • Primary Care Medicine

Background:

  • Constipation, diarrhea, and irritable bowel syndrome (IBS) are prevalent in primary care settings.
  • Many cases of constipation and diarrhea are benign and resolve without intervention.

Purpose of the Study:

  • To outline diagnostic and management strategies for chronic constipation and diarrhea in primary care.
  • To highlight the characteristics and management of irritable bowel syndrome.

Main Methods:

  • Review of common gastrointestinal complaints in primary care.
  • Clinical evaluation for organic disease in chronic constipation.
  • Clinical diagnosis for chronic diarrhea, identifying common causes.

Main Results:

  • Chronic constipation necessitates screening for organic disease, followed by dietary modification and fiber.
  • Common causes of chronic diarrhea include IBS, inflammatory bowel disease, and lactose intolerance.
  • Irritable bowel syndrome is a functional disorder managed through physician-patient relationships and medication.

Conclusions:

  • Effective management of chronic constipation and diarrhea relies on appropriate diagnostic evaluation and targeted therapies.
  • Irritable bowel syndrome requires a patient-centered approach combining medical and behavioral interventions.