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[Effect of maternal smoking on offspring growth]
G Salazar1, C García, R Berlanga
1Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago de Chile.
Insights
Maternal smoking significantly impacts infant growth. Even at three months, babies born to mothers who smoke weigh less than those born to non-smoking mothers, highlighting risks of passive smoking.
Area of Science:
- Pediatrics
- Environmental Health
- Toxicology
Context:
- Maternal smoking during pregnancy and postpartum is a significant public health concern.
- Infant growth and development are sensitive indicators of environmental exposures.
- Breast milk is a primary source of nutrition for infants, and its composition can be affected by maternal lifestyle.
Purpose:
- To investigate the impact of maternal smoking on the growth trajectory of exclusively breastfed infants up to three months of age.
- To objectively assess maternal smoking exposure and nicotine transfer to infants using urinary cotinine levels.
- To compare the growth parameters of infants born to smoking versus non-smoking mothers.
Summary:
- This study compared the growth of 20 infants (10 from smoking mothers, 10 from non-smoking mothers) exclusively breastfed for one month.
- Urinary cotinine levels confirmed higher exposure in smoking mothers and their infants, indicating nicotine transfer.
- At three months, infants of non-smoking mothers exhibited significantly higher average weight compared to infants of smoking mothers.
Impact:
- Urinary cotinine levels serve as a reliable biomarker for quantifying maternal smoking and assessing infant exposure to nicotine.
- The findings underscore the adverse effects of maternal smoking on infant growth, even in exclusively breastfed infants.
- This research highlights the importance of smoking cessation interventions for maternal and child health, emphasizing the risks of passive smoke exposure.
Background:
Maternal smoking negatively affects birth weight, breast milk volume and growth at one month of age.
Aim:
To study the effect of maternal smoking on the growth of three month old infants.
Subjects And Methods:
Ten smoking and 10 non smoking mothers with one month old children, under exclusive breast feeding, were selected for the study. Urinary cotinine levels in the mothers and children were measured to assess smoking. Two months later, children were reassessed.
Results:
Smoking mothers consumed a mean of 6.5 cigarettes/day. Compared to non smokers, urinary cotinine levels were higher in these mothers (60 +/- 21 and 1428 +/- 716 ng/ml respectively, p < 0.001) and their offspring (21 +/- 20 and 156 +/- 101 ng/ml respectively p < 0.001). Compared with smokers, at three months of age, children of non smoking mothers had a higher average weight (5829 +/- 498 and 6325 +/- 427 g, p < 0.02).
Conclusions:
Measurement of urinary cotinine levels is a reliable and objective measure of maternal smoking and nicotine transfer to the offspring. It also allows the assessment of passive smoking. Maternal smoking adversely affects child growth at three months of age.
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