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Group A streptococcal necrotizing fasciitis after varicella: report of two cases

P C Lin1, M J Lee, W Yang

  • 1Department of Pediatrics, Taipei Municipal Yang-Ming Hospital, Taiwan.

Zhonghua Minguo Xiao Er Ke Yi Xue Hui Za Zhi [Journal]. Zhonghua Minguo Xiao Er Ke Yi Xue Hui
|February 2, 1999
PubMed

Insights

Varicella (chickenpox) can lead to severe Group A beta-hemolytic streptococci (GABHS) necrotizing fasciitis. Prompt diagnosis and treatment of this GABHS superinfection are crucial for survival and limb preservation in children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Dermatology

Background:

  • Varicella (chickenpox) is a common childhood illness.
  • Cutaneous superimposed infections are frequent varicella complications.
  • Group A beta-hemolytic streptococci (GABHS) necrotizing fasciitis is a rare but severe complication of varicella.

Observation:

  • Two pediatric cases of GABHS necrotizing fasciitis secondary to varicella are presented.
  • The literature on this specific association was reviewed.
  • Delayed diagnosis of GABHS superinfection can lead to fatal outcomes.

Findings:

  • GABHS necrotizing fasciitis results from superinfection of varicella skin lesions.
  • Early recognition and aggressive management are key to patient survival.
  • Prompt intervention allowed both presented patients to survive without limb loss.

Implications:

  • Highlights the importance of vigilance for GABHS superinfection in children with varicella.
  • Emphasizes the need for prompt surgical and medical treatment to prevent severe morbidity and mortality.
  • Informs clinical practice regarding the recognition and management of severe bacterial superinfections complicating varicella.

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