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Recent developments in respiratory care pharmacology

J L Rau1

  • 1Cardiopulmonary Care Sciences, College of Health and Human Sciences, Georgia State University, Atlanta 30303, USA.

Journal of Perianesthesia Nursing : Official Journal of the American Society of Perianesthesia Nurses
|February 6, 1999
PubMed
Summary

Inhaled aerosol drugs deliver medication directly to the lungs, minimizing side effects. This review covers major respiratory drug classes and new agents for improved respiratory care.

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Area of Science:

  • Pulmonology
  • Pharmacology
  • Drug Delivery Systems

Background:

  • Inhaled aerosol drugs offer targeted respiratory treatment, reducing systemic exposure and side effects.
  • Common inhaler devices (metered dose inhaler, small volume nebulizer, dry powder inhaler) deliver a consistent lung dose fraction (approximately 10%).

Purpose of the Study:

  • To review major classes of bronchoactive inhaled drugs.
  • To identify and describe new agents within each drug class.
  • To outline clinical uses and common side effects of inhaled respiratory medications.

Main Methods:

  • Literature review of bronchoactive inhaled aerosol drugs.
  • Categorization of drugs into major respiratory groups.
  • Identification of new agents, their clinical applications, and side effects.

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Main Results:

  • Key respiratory drug groups reviewed include beta-adrenergic and anticholinergic bronchodilators, mucolytics, corticosteroids, mediator antagonists, anti-infectives, and surfactants.
  • Newer agents within these classes are identified and summarized.
  • Clinical applications and common side effects for each drug class are detailed.

Conclusions:

  • Inhaled medications provide targeted delivery to the respiratory tract.
  • Understanding different drug classes, new agents, and their side effect profiles is crucial for effective respiratory therapy.