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Alberto Gobbi

Showing results (101-110 of 124) with videos related to

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Bioorganic & Medicinal Chemistry Letters|August 16, 2016
Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME propertiesOlivier René, Benjamin P Fauber, Adrian Barnard, et al.
Nature|January 6, 2009
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cellsAndrea Viale, Francesca De Franco, Annette Orleth, et al.
Molecular and Cellular Biology|July 18, 2019
Correction for Danovi et al., "Amplification of <i>Mdmx</i> (or <i>Mdm4</i>) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity"Davide Danovi, Erik Meulmeester, Diego Pasini, et al.
Molecular and Cellular Biology|June 17, 2004
Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activityDavide Danovi, Erik Meulmeester, Diego Pasini, et al.
Bioorganic & Medicinal Chemistry Letters|November 19, 2013
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORcBenjamin P Fauber, Gladys de Leon Boenig, Brenda Burton, et al.
Blood|September 28, 2002
PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitorsSaverio Minucci, Silvia Monestiroli, Sabrina Giavara, et al.
Journal of Medicinal Chemistry|June 11, 2015
Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonistBenjamin P Fauber, Olivier René, Yuzhong Deng, et al.
Bioorganic & Medicinal Chemistry Letters|July 15, 2014
Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonistsBenjamin P Fauber, Olivier René, Gladys de Leon Boenig, et al.
ACS Medicinal Chemistry Letters|March 28, 2015
Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of ActionOlivier René, Benjamin P Fauber, Gladys de Leon Boenig, et al.
Bioorganic & Medicinal Chemistry Letters|June 7, 2015
Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonistsBenjamin P Fauber, Alberto Gobbi, Kirk Robarge, et al.
Pageof 13

Showing results (101-110 of 124) with videos related to

Sort By:
Pageof 13
Bioorganic & Medicinal Chemistry Letters|August 16, 2016
Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME propertiesOlivier René, Benjamin P Fauber, Adrian Barnard, et al.
Nature|January 6, 2009
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cellsAndrea Viale, Francesca De Franco, Annette Orleth, et al.
Molecular and Cellular Biology|July 18, 2019
Correction for Danovi et al., "Amplification of <i>Mdmx</i> (or <i>Mdm4</i>) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity"Davide Danovi, Erik Meulmeester, Diego Pasini, et al.
Molecular and Cellular Biology|June 17, 2004
Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activityDavide Danovi, Erik Meulmeester, Diego Pasini, et al.
Bioorganic & Medicinal Chemistry Letters|November 19, 2013
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORcBenjamin P Fauber, Gladys de Leon Boenig, Brenda Burton, et al.
Blood|September 28, 2002
PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitorsSaverio Minucci, Silvia Monestiroli, Sabrina Giavara, et al.
Journal of Medicinal Chemistry|June 11, 2015
Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonistBenjamin P Fauber, Olivier René, Yuzhong Deng, et al.
Bioorganic & Medicinal Chemistry Letters|July 15, 2014
Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonistsBenjamin P Fauber, Olivier René, Gladys de Leon Boenig, et al.
ACS Medicinal Chemistry Letters|March 28, 2015
Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of ActionOlivier René, Benjamin P Fauber, Gladys de Leon Boenig, et al.
Bioorganic & Medicinal Chemistry Letters|June 7, 2015
Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonistsBenjamin P Fauber, Alberto Gobbi, Kirk Robarge, et al.
Pageof 13