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Biochemistry|April 15, 2015
Measuring propargyl-linked drug populations inside bacterial cells, and their interaction with a dihydrofolate reductase target, by Raman microscopyHossein Heidari-Torkabadi, Tao Che, Michael N Lombardo, et al.
Organic Letters|January 27, 2006
Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditionsJasmina Nikodinovic, Jennifer M Dinges, Stephen C Bergmeier, et al.
Journal of Molecular Biology|March 3, 2009
Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistanceKathleen M Frey, Jieying Liu, Michael N Lombardo, et al.
Antimicrobial Agents and Chemotherapy|October 8, 2014
Crystal structures of Klebsiella pneumoniae dihydrofolate reductase bound to propargyl-linked antifolates reveal features for potency and selectivityKristen M Lamb, Michael N Lombardo, Jeremy Alverson, et al.
Organic Letters|December 14, 2016
Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building BlocksNarendran G-Dayanandan, Eric W Scocchera, Santosh Keshipeddy, et al.
Bioorganic & Medicinal Chemistry Letters|October 9, 2012
Viridin analogs derived from steroidal building blocksKishore Viswanathan, Sophia N Ononye, Harold D Cooper, et al.
Chemical Biology & Drug Design|January 21, 2009
Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitorsJieying Liu, David B Bolstad, Adrienne E Smith, et al.
Chemistry & Biology|September 23, 2008
Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductaseJieying Liu, David B Bolstad, Adrienne E Smith, et al.
Mbio|January 25, 2022
Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human HerpesvirusesKatherine A DiScipio, Savithri Weerasooriya, Renata Szczepaniak, et al.
Bioorganic & Medicinal Chemistry Letters|June 6, 2006
Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivativeVeljko M Popov, David C M Chan, Yale A Fillingham, et al.
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