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Don O Somers

Showing results (1-10 of 17) with videos related to

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Journal of Chemical Information and Modeling|January 8, 2020
Exploring Ligand Stability in Protein Crystal Structures Using Binding Pose MetadynamicsLucia Fusani, David S Palmer, Don O Somers, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA<sub>2</sub> InhibitorNicholas D Measom, Kenneth D Down, David J Hirst, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2008
Kinase array design, back to front: biaryl amidesIan Baldwin, Paul Bamborough, Claudine G Haslam, et al.
RSC Chemical Biology|November 30, 2023
Covalent targeting of non-cysteine residues in PI4KIIIβBrett Cosgrove, Emma K Grant, Sophie Bertrand, et al.
Bioorganic & Medicinal Chemistry|June 16, 2009
Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding modeMichael Kranz, Michael Wall, Brian Evans, et al.
Bioorganic & Medicinal Chemistry Letters|July 11, 2008
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activityRichard Angell, Nicola M Aston, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters|November 6, 2007
Biphenyl amide p38 kinase inhibitors 2: Optimisation and SARRichard M Angell, Tony D Angell, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters|February 7, 2009
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administrationChristopher J Lunniss, Anthony W J Cooper, Colin D Eldred, et al.
Bioorganic & Medicinal Chemistry Letters|July 8, 2008
Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modesRichard M Angell, Tony D Angell, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2016
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitorsNeil S Garton, Michael D Barker, Rob P Davis, et al.
Pageof 2

Showing results (1-10 of 17) with videos related to

Sort By:
Pageof 2
Journal of Chemical Information and Modeling|January 8, 2020
Exploring Ligand Stability in Protein Crystal Structures Using Binding Pose MetadynamicsLucia Fusani, David S Palmer, Don O Somers, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA<sub>2</sub> InhibitorNicholas D Measom, Kenneth D Down, David J Hirst, et al.
Bioorganic & Medicinal Chemistry Letters|September 16, 2008
Kinase array design, back to front: biaryl amidesIan Baldwin, Paul Bamborough, Claudine G Haslam, et al.
RSC Chemical Biology|November 30, 2023
Covalent targeting of non-cysteine residues in PI4KIIIβBrett Cosgrove, Emma K Grant, Sophie Bertrand, et al.
Bioorganic & Medicinal Chemistry|June 16, 2009
Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding modeMichael Kranz, Michael Wall, Brian Evans, et al.
Bioorganic & Medicinal Chemistry Letters|July 11, 2008
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activityRichard Angell, Nicola M Aston, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters|November 6, 2007
Biphenyl amide p38 kinase inhibitors 2: Optimisation and SARRichard M Angell, Tony D Angell, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters|February 7, 2009
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administrationChristopher J Lunniss, Anthony W J Cooper, Colin D Eldred, et al.
Bioorganic & Medicinal Chemistry Letters|July 8, 2008
Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modesRichard M Angell, Tony D Angell, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters|September 1, 2016
Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitorsNeil S Garton, Michael D Barker, Rob P Davis, et al.
Pageof 2