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Neurobiology of Pain (Cambridge, Mass.)
|
April 11, 2025
Humanized Na<sub>V</sub>1.8 rats overcome cross-species potency shifts in developing novel Na<sub>V</sub>1.8 inhibitors
Dillon S McDevitt, Joshua D Vardigan, Xiaoping Zhou, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Macrocyclic inhibitors of beta-secretase: functional activity in an animal model
Shawn J Stachel, Craig A Coburn, Sethu Sankaranarayanan, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 4, 2010
Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors
Hong Zhu, Mary B Young, Philippe G Nantermet, et al.
Journal of Medicinal Chemistry
|
June 23, 2007
Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid
Matthew G Stanton, Shaun R Stauffer, Alison R Gregro, et al.
The Journal of Biological Chemistry
|
March 2, 2005
Compounds that bind APP and inhibit Abeta processing in vitro suggest a novel approach to Alzheimer disease therapeutics
Amy S Espeseth, Min Xu, Qian Huang, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 8, 2007
Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors
Stacey R Lindsley, Keith P Moore, Hemaka A Rajapakse, et al.
Journal of Medicinal Chemistry
|
September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase
James C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 16, 2008
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primates
Sethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, et al.
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of 2
Search research articles
Search
Showing results (11-20 of 18) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 18 results.
Neurobiology of Pain (Cambridge, Mass.)
|
April 11, 2025
Humanized Na<sub>V</sub>1.8 rats overcome cross-species potency shifts in developing novel Na<sub>V</sub>1.8 inhibitors
Dillon S McDevitt, Joshua D Vardigan, Xiaoping Zhou, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Macrocyclic inhibitors of beta-secretase: functional activity in an animal model
Shawn J Stachel, Craig A Coburn, Sethu Sankaranarayanan, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 4, 2010
Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors
Hong Zhu, Mary B Young, Philippe G Nantermet, et al.
Journal of Medicinal Chemistry
|
June 23, 2007
Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid
Matthew G Stanton, Shaun R Stauffer, Alison R Gregro, et al.
The Journal of Biological Chemistry
|
March 2, 2005
Compounds that bind APP and inhibit Abeta processing in vitro suggest a novel approach to Alzheimer disease therapeutics
Amy S Espeseth, Min Xu, Qian Huang, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 8, 2007
Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors
Stacey R Lindsley, Keith P Moore, Hemaka A Rajapakse, et al.
Journal of Medicinal Chemistry
|
September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase
James C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
October 16, 2008
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primates
Sethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, et al.
Page
of 2