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Structure (London, England : 1993)|December 23, 2025
Mechanism of SHP2 activation by bis-Tyr-phosphorylated Gab1Lisa Machner, Alaa Shaikhqasem, Tobias Gruber, et al.Communications Chemistry|January 27, 2023
A small-molecule inhibitor of lectin-like oxidized LDL receptor-1 acts by stabilizing an inactive receptor tetramer stateGisela Schnapp, Heike Neubauer, Frank H Büttner, et al.Proceedings of the National Academy of Sciences of the United States of America|July 21, 2012
Molecular basis of β-amyloid oligomer recognition with a conformational antibody fragmentIsabel Morgado, Karin Wieligmann, Magdalena Bereza, et al.SLAS Discovery : Advancing Life Sciences R & D|October 19, 2020
MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein-Ligand Interactions at High ThroughputRoman P Simon, Martin Winter, Carola Kleiner, et al.Chemmedchem|August 12, 2015
One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit ListsJohannes Schiebel, Nedyalka Radeva, Helene Köster, et al.Journal of Medicinal Chemistry|September 13, 2018
Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like MoleculeChristofer S Tautermann, Florian Binder, Frank H Büttner, et al.Biorxiv : the Preprint Server for Biology|January 7, 2026
Tuning the open-close equilibrium of Cereblon with small molecules influences protein degradationSuzanne O'Connor, Zoe J Rutter, Angus D Cowan, et al.Journal of Medicinal Chemistry|February 26, 2016
Structure-Based Design of an in Vivo Active Selective BRD9 InhibitorLaetitia J Martin, Manfred Koegl, Gerd Bader, et al.Chemmedchem|December 4, 2020
Getting a Grip on the Undrugged: Targeting β-Catenin with Fragment-Based MethodsDirk Kessler, Moriz Mayer, Stephan K Zahn, et al.Proceedings of the National Academy of Sciences of the United States of America|July 24, 2019
Drugging an undruggable pocket on KRASDirk Kessler, Michael Gmachl, Andreas Mantoulidis, et al.Pageof 13