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Michael D Altman

Showing results (21-30 of 45) with videos related to

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Bioorganic & Medicinal Chemistry Letters|September 26, 2015
Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modificationsJongwon Lim, Michael D Altman, James Baker, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2019
Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflowXavier Fradera, Joey L Methot, Abdelghani Achab, et al.
Journal of the American Chemical Society|April 17, 2008
HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variantsMichael D Altman, Akbar Ali, G S Kiran Kumar Reddy, et al.
ACS Medicinal Chemistry Letters|January 19, 2019
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STINGTony Siu, Michael D Altman, Gretchen A Baltus, et al.
Bioorganic & Medicinal Chemistry Letters|June 28, 2020
Corrigendum to "Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow" [Bioorg. Med. Chem. Lett. 29 (2019) 2575-2580]Xavier Fradera, Joey L Methot, Abdelghani Achab, et al.
Journal of Medicinal Chemistry|September 28, 2011
Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disordersJongwon Lim, Brandon Taoka, Ryan D Otte, et al.
Bioorganic & Medicinal Chemistry Letters|April 18, 2021
Discovery of a new series of PI3K-δ inhibitors from Virtual ScreeningXavier Fradera, Qiaolin Deng, Abdelganhi Achab, et al.
Bioorganic & Medicinal Chemistry Letters|August 6, 2016
Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical propertiesDavid L Sloman, Njamkou Noucti, Michael D Altman, et al.
Bioorganic & Medicinal Chemistry Letters|November 30, 2016
MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentationAndrew M Haidle, Kaleen K Childers, Anna A Zabierek, et al.
ACS Chemical Biology|August 15, 2017
Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate ReductaseJohn P Santa Maria, Yumi Park, Lihu Yang, et al.
Pageof 5

Showing results (21-30 of 45) with videos related to

Sort By:
Pageof 5
Bioorganic & Medicinal Chemistry Letters|September 26, 2015
Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modificationsJongwon Lim, Michael D Altman, James Baker, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2019
Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflowXavier Fradera, Joey L Methot, Abdelghani Achab, et al.
Journal of the American Chemical Society|April 17, 2008
HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variantsMichael D Altman, Akbar Ali, G S Kiran Kumar Reddy, et al.
ACS Medicinal Chemistry Letters|January 19, 2019
Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STINGTony Siu, Michael D Altman, Gretchen A Baltus, et al.
Bioorganic & Medicinal Chemistry Letters|June 28, 2020
Corrigendum to "Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow" [Bioorg. Med. Chem. Lett. 29 (2019) 2575-2580]Xavier Fradera, Joey L Methot, Abdelghani Achab, et al.
Journal of Medicinal Chemistry|September 28, 2011
Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disordersJongwon Lim, Brandon Taoka, Ryan D Otte, et al.
Bioorganic & Medicinal Chemistry Letters|April 18, 2021
Discovery of a new series of PI3K-δ inhibitors from Virtual ScreeningXavier Fradera, Qiaolin Deng, Abdelganhi Achab, et al.
Bioorganic & Medicinal Chemistry Letters|August 6, 2016
Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical propertiesDavid L Sloman, Njamkou Noucti, Michael D Altman, et al.
Bioorganic & Medicinal Chemistry Letters|November 30, 2016
MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentationAndrew M Haidle, Kaleen K Childers, Anna A Zabierek, et al.
ACS Chemical Biology|August 15, 2017
Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate ReductaseJohn P Santa Maria, Yumi Park, Lihu Yang, et al.
Pageof 5