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Molecular Biosystems
|
December 13, 2006
Fragment screening: an introduction
Andrew R Leach, Michael M Hann, Jeremy N Burrows, et al.
Medchemcomm
|
August 16, 2018
Approaches to target tractability assessment - a practical perspective
Kristin K Brown, Michael M Hann, Ami S Lakdawala, et al.
Journal of Medicinal Chemistry
|
April 29, 2016
Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia
György M Keserű, Daniel A Erlanson, György G Ferenczy, et al.
Biochimica Et Biophysica Acta
|
July 23, 2013
Unlocking the secrets of the gatekeeper: methods for stabilizing and crystallizing GPCRs
Nicolas Bertheleme, Pil Seok Chae, Shweta Singh, et al.
Journal of Biomolecular Screening
|
September 5, 2015
Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability
Laurie J Gordon, Morven Allen, Per Artursson, et al.
RSC Medicinal Chemistry
|
May 1, 2023
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry
Ross P Thomas, Emma K Grant, Eleanor R Dickinson, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 14, 2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
André Mateus, Laurie J Gordon, Gareth J Wayne, et al.
Chemical Science
|
October 20, 2021
A direct-to-biology high-throughput chemistry approach to reactive fragment screening
Ross P Thomas, Rachel E Heap, Francesca Zappacosta, et al.
Nature Reviews. Drug Discovery
|
July 21, 2021
The PROTACtable genome
Melanie Schneider, Chris J Radoux, Andrew Hercules, et al.
Angewandte Chemie (International Ed. in English)
|
August 4, 2020
A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands
Emma K Grant, David J Fallon, Michael M Hann, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 25) with videos related to
Sort By:
Page
of 3
Molecular Biosystems
|
December 13, 2006
Fragment screening: an introduction
Andrew R Leach, Michael M Hann, Jeremy N Burrows, et al.
Medchemcomm
|
August 16, 2018
Approaches to target tractability assessment - a practical perspective
Kristin K Brown, Michael M Hann, Ami S Lakdawala, et al.
Journal of Medicinal Chemistry
|
April 29, 2016
Design Principles for Fragment Libraries: Maximizing the Value of Learnings from Pharma Fragment-Based Drug Discovery (FBDD) Programs for Use in Academia
György M Keserű, Daniel A Erlanson, György G Ferenczy, et al.
Biochimica Et Biophysica Acta
|
July 23, 2013
Unlocking the secrets of the gatekeeper: methods for stabilizing and crystallizing GPCRs
Nicolas Bertheleme, Pil Seok Chae, Shweta Singh, et al.
Journal of Biomolecular Screening
|
September 5, 2015
Direct Measurement of Intracellular Compound Concentration by RapidFire Mass Spectrometry Offers Insights into Cell Permeability
Laurie J Gordon, Morven Allen, Per Artursson, et al.
RSC Medicinal Chemistry
|
May 1, 2023
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry
Ross P Thomas, Emma K Grant, Eleanor R Dickinson, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 14, 2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery
André Mateus, Laurie J Gordon, Gareth J Wayne, et al.
Chemical Science
|
October 20, 2021
A direct-to-biology high-throughput chemistry approach to reactive fragment screening
Ross P Thomas, Rachel E Heap, Francesca Zappacosta, et al.
Nature Reviews. Drug Discovery
|
July 21, 2021
The PROTACtable genome
Melanie Schneider, Chris J Radoux, Andrew Hercules, et al.
Angewandte Chemie (International Ed. in English)
|
August 4, 2020
A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands
Emma K Grant, David J Fallon, Michael M Hann, et al.
Page
of 3