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Journal of the American Chemical Society|March 19, 2015
Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1Changwook Lee, Hye-Kyung Park, Hanbin Jeong, et al.Nature Metabolism|January 12, 2024
p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSLHwang Chan Yu, Yong Geun Jeon, Ann-Yae Na, et al.Hepatology (Baltimore, Md.)|February 2, 2022
p21-activated kinase 4 inhibition protects against liver ischemia/reperfusion injury: Role of nuclear factor erythroid 2-related factor 2 phosphorylationYuancheng Mao, Chang Yeob Han, Lihua Hao, et al.Cell Death Discovery|October 13, 2025
Apomorphine is a novel necroptosis inhibitor targeting mixed lineage kinase domain-like protein oligomerizationMyeonggil Han, Dong-Hyun Seo, Man Sup Kwak, et al.Oncotarget|October 21, 2017
A small-molecule inhibitor targeting the AURKC-IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cellsEun Hee Han, Jin-Young Min, Shin-Ae Yoo, et al.Cancer Discovery|October 4, 2016
Acquired METD1228V Mutation and Resistance to MET Inhibition in Lung CancerMagda Bahcall, Taebo Sim, Cloud P Paweletz, et al.Cell Chemical Biology|April 2, 2019
Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family SpecificityFleur M Ferguson, Zainab M Doctor, Scott B Ficarro, et al.Nature Communications|November 3, 2025
Targeting cancer glutamine dependency with a first-in-class inhibitor of the mitochondrial glutamine transporter SLC1A5_varYulseung Sung, Ya Chun Yu, Mirim Lee, et al.Biochemical Pharmacology|January 22, 2026
Gut microbiota-derived isoxanthohumol metabolite, 8-prenylnaringenin, mitigates endothelial dysfunction in Angiotensin II-induced hypertension through G protein-coupled estrogen receptor-mediated eNOS activationSeung Yeon Lee, Anh Thi Ngoc Bui, Tuyet Ngan Thai, et al.Angewandte Chemie (International Ed. in English)|November 22, 2013
Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitorSang Min Lim, Kenneth D Westover, Scott B Ficarro, et al.Pageof 11