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Journal of Medicinal Chemistry
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January 23, 2016
Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19
Aurélie Mallinger, Kai Schiemann, Christian Rink, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
Matthew D Cheeseman, Nicola E A Chessum, Carl S Rye, et al.
Nature Reviews. Clinical Oncology
|
February 9, 2019
Challenges to curing primary brain tumours
Kenneth Aldape, Kevin M Brindle, Louis Chesler, et al.
Nature Reviews. Clinical Oncology
|
June 1, 2019
Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'
Kenneth Aldape, Kevin M Brindle, Louis Chesler, et al.
Gut
|
September 14, 2016
Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers
Pietro Carotenuto, Matteo Fassan, Rosantony Pandolfo, et al.
Nature Chemical Biology
|
October 27, 2015
A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease
Trevor Dale, Paul A Clarke, Christina Esdar, et al.
Gastroenterology
|
November 9, 2017
MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma
Andrea Lampis, Pietro Carotenuto, Georgios Vlachogiannis, et al.
Elife
|
December 10, 2016
Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases
Paul A Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele, et al.
Journal of Medicinal Chemistry
|
February 14, 2015
Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen
Aurélie Mallinger, Simon Crumpler, Mark Pichowicz, et al.
Journal of Medicinal Chemistry
|
July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone
Paul A Brough, Xavier Barril, Jenifer Borgognoni, et al.
Page
of 32
Search research articles
Search
Showing results (291-300 of 315) with videos related to
Sort By:
Page
of 32
Journal of Medicinal Chemistry
|
January 23, 2016
Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19
Aurélie Mallinger, Kai Schiemann, Christian Rink, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
Matthew D Cheeseman, Nicola E A Chessum, Carl S Rye, et al.
Nature Reviews. Clinical Oncology
|
February 9, 2019
Challenges to curing primary brain tumours
Kenneth Aldape, Kevin M Brindle, Louis Chesler, et al.
Nature Reviews. Clinical Oncology
|
June 1, 2019
Reply to 'Assembling the brain trust: the multidisciplinary imperative in neuro-oncology'
Kenneth Aldape, Kevin M Brindle, Louis Chesler, et al.
Gut
|
September 14, 2016
Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers
Pietro Carotenuto, Matteo Fassan, Rosantony Pandolfo, et al.
Nature Chemical Biology
|
October 27, 2015
A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease
Trevor Dale, Paul A Clarke, Christina Esdar, et al.
Gastroenterology
|
November 9, 2017
MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma
Andrea Lampis, Pietro Carotenuto, Georgios Vlachogiannis, et al.
Elife
|
December 10, 2016
Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases
Paul A Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele, et al.
Journal of Medicinal Chemistry
|
February 14, 2015
Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen
Aurélie Mallinger, Simon Crumpler, Mark Pichowicz, et al.
Journal of Medicinal Chemistry
|
July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone
Paul A Brough, Xavier Barril, Jenifer Borgognoni, et al.
Page
of 32