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The Journal of Biological Chemistry|February 1, 2021
Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activityJacob I Stuckey, Nico R Cantone, Alexandre Côté, et al.ACS Medicinal Chemistry Letters|June 20, 2020
Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence TimeAvinash Khanna, Alexandre Côté, Shilpi Arora, et al.The Journal of Biological Chemistry|May 12, 2007
Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulationTimothy S Fisher, Paola Lo Surdo, Shilpa Pandit, et al.The Journal of Biological Chemistry|November 13, 2008
Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutantsMatthew J Bottomley, Agostino Cirillo, Laura Orsatti, et al.Bioorganic & Medicinal Chemistry Letters|August 9, 2016
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitorsSharada S Labadie, Peter S Dragovich, Richard T Cummings, et al.Bioorganic & Medicinal Chemistry Letters|December 13, 2005
The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infectionYusheng Xiong, Judyann Wiltsie, Andrea Woods, et al.Bioorganic & Medicinal Chemistry Letters|July 20, 2015
Discovery, design, and synthesis of indole-based EZH2 inhibitorsVictor S Gehling, Rishi G Vaswani, Christopher G Nasveschuk, et al.Bioorganic & Medicinal Chemistry Letters|August 2, 2016
Identification of potent, selective KDM5 inhibitorsVictor S Gehling, Steven F Bellon, Jean-Christophe Harmange, et al.ACS Medicinal Chemistry Letters|June 20, 2020
Design and Synthesis of Styrenylcyclopropylamine LSD1 InhibitorsVictor S Gehling, John P McGrath, Martin Duplessis, et al.ACS Medicinal Chemistry Letters|March 18, 2016
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET BromodomainsAlexander M Taylor, Rishi G Vaswani, Victor S Gehling, et al.Pageof 3