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The Journal of Pharmacology and Experimental Therapeutics
|
December 25, 2007
In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1
Sethu Sankaranarayanan, Eric A Price, Guoxin Wu, et al.
BMC Neuroscience
|
November 9, 2010
Viable mouse gene ablations that robustly alter brain Aβ levels are rare
Jeremy H Toyn, Xu-Alan Lin, Mark W Thompson, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2007
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors
Keith P Moore, Hong Zhu, Hemaka A Rajapakse, et al.
Neuron
|
March 31, 2005
Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex
Philip E Brandish, Ming Su, Daniel J Holder, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Macrocyclic inhibitors of beta-secretase: functional activity in an animal model
Shawn J Stachel, Craig A Coburn, Sethu Sankaranarayanan, et al.
Plos One
|
August 26, 2014
Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease
Paul D Wes, Amy Easton, John Corradi, et al.
Journal of Neurology, Neurosurgery, and Psychiatry
|
June 6, 2014
Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy
Dana Wagshal, Sethu Sankaranarayanan, Valerie Guss, et al.
Science (New York, N.Y.)
|
September 13, 2021
Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury
Stephanie S Holden, Fiorella C Grandi, Oumaima Aboubakr, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 4, 2010
Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors
Hong Zhu, Mary B Young, Philippe G Nantermet, et al.
Journal of Medicinal Chemistry
|
June 23, 2007
Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid
Matthew G Stanton, Shaun R Stauffer, Alison R Gregro, et al.
Page
of 4
Search research articles
Search
Showing results (21-30 of 40) with videos related to
Sort By:
Page
of 4
The Journal of Pharmacology and Experimental Therapeutics
|
December 25, 2007
In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1
Sethu Sankaranarayanan, Eric A Price, Guoxin Wu, et al.
BMC Neuroscience
|
November 9, 2010
Viable mouse gene ablations that robustly alter brain Aβ levels are rare
Jeremy H Toyn, Xu-Alan Lin, Mark W Thompson, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2007
Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors
Keith P Moore, Hong Zhu, Hemaka A Rajapakse, et al.
Neuron
|
March 31, 2005
Regulation of gene expression by lithium and depletion of inositol in slices of adult rat cortex
Philip E Brandish, Ming Su, Daniel J Holder, et al.
Journal of Medicinal Chemistry
|
October 13, 2006
Macrocyclic inhibitors of beta-secretase: functional activity in an animal model
Shawn J Stachel, Craig A Coburn, Sethu Sankaranarayanan, et al.
Plos One
|
August 26, 2014
Tau overexpression impacts a neuroinflammation gene expression network perturbed in Alzheimer's disease
Paul D Wes, Amy Easton, John Corradi, et al.
Journal of Neurology, Neurosurgery, and Psychiatry
|
June 6, 2014
Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy
Dana Wagshal, Sethu Sankaranarayanan, Valerie Guss, et al.
Science (New York, N.Y.)
|
September 13, 2021
Complement factor C1q mediates sleep spindle loss and epileptic spikes after mild brain injury
Stephanie S Holden, Fiorella C Grandi, Oumaima Aboubakr, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 4, 2010
Rapid P1 SAR of brain penetrant tertiary carbinamine derived BACE inhibitors
Hong Zhu, Mary B Young, Philippe G Nantermet, et al.
Journal of Medicinal Chemistry
|
June 23, 2007
Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid
Matthew G Stanton, Shaun R Stauffer, Alison R Gregro, et al.
Page
of 4