Showing results (51-60 of 64) with videos related to
Sort By:
Pageof 7
Bioorganic & Medicinal Chemistry Letters|October 12, 2010
Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesityShuwen He, Zhixiong Ye, Peter H Dobbelaar, et al.Cell Metabolism|January 26, 2010
Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesityXiao-Ming Guan, Howard Chen, Peter H Dobbelaar, et al.Bioorganic & Medicinal Chemistry Letters|March 12, 2010
Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesityJian Liu, Shuwen He, Tianying Jian, et al.Bioorganic & Medicinal Chemistry Letters|March 9, 2010
Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonistShuwen He, Zhixiong Ye, Peter H Dobbelaar, et al.Bioorganic & Medicinal Chemistry Letters|April 7, 2019
Accelerating the discovery of DGAT1 inhibitors through the application of parallel medicinal chemistry (PMC)Yang Yu, Zhicai Wu, Zhi-Cai Shi, et al.Bioorganic & Medicinal Chemistry Letters|March 31, 2019
Benzimidazole-based DGAT1 inhibitors with a [3.1.0] bicyclohexane carboxylic acid moietyShuwen He, Zhong Lai, Qingmei Hong, et al.Bioorganic & Medicinal Chemistry Letters|July 6, 2010
Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligandsQingmei Hong, Raman K Bakshi, James Dellureficio, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Potent DGAT1 Inhibitors in the Benzimidazole Class with a Pyridyl-oxy-cyclohexanecarboxylic Acid MoietyShuwen He, Qingmei Hong, Zhong Lai, et al.ACS Medicinal Chemistry Letters|October 29, 2014
Discovery of a Potent and Selective DGAT1 Inhibitor with a Piperidinyl-oxy-cyclohexanecarboxylic Acid MoietyShuwen He, Qingmei Hong, Zhong Lai, et al.Bioorganic & Medicinal Chemistry Letters|February 20, 2010
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonistsShuwen He, Peter H Dobbelaar, Jian Liu, et al.Pageof 7