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Journal of Medicinal Chemistry
|
August 22, 2013
How to deal with low-resolution target structures: using SAR, ensemble docking, hydropathic analysis, and 3D-QSAR to definitively map the αβ-tubulin colchicine site
Chenxiao Da, Susan L Mooberry, John T Gupton, et al.
Bioorganic & Medicinal Chemistry
|
April 16, 2018
Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent
Weiguo Xiang, Shruti Choudhary, Ernest Hamel, et al.
Journal of Natural Products
|
June 17, 2016
Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer
Andrew J Robles, Lin Du, Robert H Cichewicz, et al.
Journal of Medicinal Chemistry
|
July 27, 2011
Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agents
Aleem Gangjee, Ying Zhao, Ernest Hamel, et al.
Journal of Natural Products
|
January 21, 2012
Amyrisins A-C, O-prenylated flavonoids from Amyris madrensis
Jiangnan Peng, Rachel M Hartley, Gary A Fest, et al.
Organic Letters
|
March 28, 2006
Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue
Paul A Wender, Michael K Hilinski, Nicolas Soldermann, et al.
Breast Cancer Research and Treatment
|
June 4, 2016
Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer
Andrew J Robles, Shengxin Cai, Robert H Cichewicz, et al.
Molecular Pharmaceutics
|
July 30, 2008
Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy
Susan L Mooberry, Michael K Hilinski, Erin A Clark, et al.
Natural Product Communications
|
April 3, 2014
Antiproliferative effects of 12-oxoheteronemin vs heteronemin
Siriporn Kittiwisut, Cristina C Rohena, Supreeya Yuenyongsawad, et al.
Steroids
|
November 21, 2002
Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs
Pemmaraju N Rao, James W Cessac, Tina L Tinley, et al.
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Search research articles
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Showing results (21-30 of 120) with videos related to
Sort By:
Page
of 12
Journal of Medicinal Chemistry
|
August 22, 2013
How to deal with low-resolution target structures: using SAR, ensemble docking, hydropathic analysis, and 3D-QSAR to definitively map the αβ-tubulin colchicine site
Chenxiao Da, Susan L Mooberry, John T Gupton, et al.
Bioorganic & Medicinal Chemistry
|
April 16, 2018
Structure based drug design and in vitro metabolism study: Discovery of N-(4-methylthiophenyl)-N,2-dimethyl-cyclopenta[d]pyrimidine as a potent microtubule targeting agent
Weiguo Xiang, Shruti Choudhary, Ernest Hamel, et al.
Journal of Natural Products
|
June 17, 2016
Maximiscin Induces DNA Damage, Activates DNA Damage Response Pathways, and Has Selective Cytotoxic Activity against a Subtype of Triple-Negative Breast Cancer
Andrew J Robles, Lin Du, Robert H Cichewicz, et al.
Journal of Medicinal Chemistry
|
July 27, 2011
Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agents
Aleem Gangjee, Ying Zhao, Ernest Hamel, et al.
Journal of Natural Products
|
January 21, 2012
Amyrisins A-C, O-prenylated flavonoids from Amyris madrensis
Jiangnan Peng, Rachel M Hartley, Gary A Fest, et al.
Organic Letters
|
March 28, 2006
Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue
Paul A Wender, Michael K Hilinski, Nicolas Soldermann, et al.
Breast Cancer Research and Treatment
|
June 4, 2016
Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer
Andrew J Robles, Shengxin Cai, Robert H Cichewicz, et al.
Molecular Pharmaceutics
|
July 30, 2008
Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy
Susan L Mooberry, Michael K Hilinski, Erin A Clark, et al.
Natural Product Communications
|
April 3, 2014
Antiproliferative effects of 12-oxoheteronemin vs heteronemin
Siriporn Kittiwisut, Cristina C Rohena, Supreeya Yuenyongsawad, et al.
Steroids
|
November 21, 2002
Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs
Pemmaraju N Rao, James W Cessac, Tina L Tinley, et al.
Page
of 12