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Plos Computational Biology|September 25, 2020
A greedy classifier optimization strategy to assess ion channel blocking activity and pro-arrhythmia in hiPSC-cardiomyocytesFabien Raphel, Tessa De Korte, Damiano Lombardi, et al.Journal of Pharmacological and Toxicological Methods|June 28, 2021
Safety pharmacology during the COVID pandemicMichael K Pugsley, Yevgeniya Koshman, Tessa de Korte, et al.Journal of Pharmacological and Toxicological Methods|June 30, 2019
Methodological and technological advances in safety pharmacology - New or simply nuanced?Michael K Pugsley, Tessa de Korte, Venkatesha Udupa, et al.Journal of Pharmacological and Toxicological Methods|May 3, 2017
Safety pharmacology methods and models in an evolving regulatory environmentMichael K Pugsley, Tessa de Korte, Simon Authier, et al.Journal of Molecular and Cellular Cardiology|September 19, 2019
Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordingsAnne Zwartsen, Tessa de Korte, Peter Nacken, et al.Journal of Pharmacological and Toxicological Methods|August 4, 2022
Safety pharmacology in 2022: Taking one small step for cardiovascular safety assay development but one giant leap for regulatory drug safety assessmentMichael K Pugsley, Yevgeniya E Koshman, Tessa de Korte, et al.Journal of Pharmacological and Toxicological Methods|January 23, 2018
Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference reportPetra Mulder, Tessa de Korte, Elena Dragicevic, et al.Journal of Pharmacological and Toxicological Methods|August 18, 2020
Twenty years of safety pharmacology model validation and the wider implications of this to drug discoveryMichael K Pugsley, Bisrat Bekele, Helene Griessel, et al.Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology|August 10, 2020
Repolarization instability and arrhythmia by IKr block in single human-induced pluripotent stem cell-derived cardiomyocytes and 2D monolayersCristina Altrocchi, Tessa de Korte, Joyce Bernardi, et al.Stem Cells (Dayton, Ohio)|April 16, 2022
Optogenetic Reporters Delivered as mRNA Facilitate Repeatable Action Potential and Calcium Handling Assessment in Human iPSC-Derived CardiomyocytesLoukia Yiangou, Albert Blanch-Asensio, Tessa de Korte, et al.Pageof 2