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CPT: Pharmacometrics & Systems Pharmacology|September 25, 2021
A multistate transition model for statin-induced myopathy and statin discontinuationYuxi Zhu, Chien-Wei Chiang, Lei Wang, et al.CPT: Pharmacometrics & Systems Pharmacology|February 22, 2022
Covariate analysis of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate, based on first-in-human studyClemence Pouzin, Michel Tod, Mustapha Chadjaa, et al.CPT: Pharmacometrics & Systems Pharmacology|June 18, 2019
Nonlinear Mixed-Effects Model Development and Simulation Using nlmixr and Related R Open-Source PackagesMatthew Fidler, Justin J Wilkins, Richard Hooijmaijers, et al.CPT: Pharmacometrics & Systems Pharmacology|June 18, 2019
Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody-Drug ConjugatesMatts Kågedal, Divya Samineni, William R Gillespie, et al.CPT: Pharmacometrics & Systems Pharmacology|April 21, 2022
Model-informed drug development of voxelotor in sickle cell disease: Population pharmacokinetics in whole blood and plasmaRadojka M Savic, Michelle L Green, Karin Jorga, et al.CPT: Pharmacometrics & Systems Pharmacology|April 21, 2022
Model-informed drug development of voxelotor in sickle cell disease: Exposure-response analysis to support dosing and confirm mechanism of actionMichelle L Green, Radojka M Savic, Margaret Tonda, et al.CPT: Pharmacometrics & Systems Pharmacology|October 1, 2021
A quantitative systems pharmacology approach to predict the safe-equivalent dose of doxorubicin in patients with cardiovascular comorbidityLan Sang, Yi Yuan, Ying Zhou, et al.CPT: Pharmacometrics & Systems Pharmacology|October 8, 2021
Development of physiologically-based pharmacokinetic models for standard of care and newer tuberculosis drugsHelen Humphries, Lisa Almond, Alexander Berg, et al.CPT: Pharmacometrics & Systems Pharmacology|October 9, 2021
Exposure-safety analysis of QTc interval and transaminase levels following bedaquiline administration in patients with drug-resistant tuberculosisLénaïg Tanneau, Elin M Svensson, Stefaan Rossenu, et al.CPT: Pharmacometrics & Systems Pharmacology|October 14, 2021
Evaluation of the estimation and classification performance of NONMEM when applying mixture model for drug clearanceKa Ho Hui, Tai Ning LamPageof 153