Helen K Boffey

4PUBLICATIONS
8CO-AUTHORS
Neurology and neuromuscular diseasesCheminformatics and quantitative structure-activity relationshipsClinical pharmacology and therapeuticsProteins and peptides
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Publications (4)

|Nov 19, 2025
Development of Purine and Pyrrolopyrimidine Scaffolds as Potent, Selective, and Brain Penetrant NUAK1 Inhibitors.

Gregory G Aldred, Helen K Boffey, Henriette M G Willems

|Feb 19, 2025
Development of the Pyrido[2,3-d]pyrimidin-7(8H)-one Scaffold toward Potent and Selective NUAK1 Inhibitors.

Timothy P C Rooney, Gregory G Aldred, David Winpenny

|Oct 20, 2023
The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K).

Gregory G Aldred, Timothy P C Rooney, Henriette M G Willems

|May 30, 2023
Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor.

Henriëtte M G Willems, Simon Edwards, Helen K Boffey

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Frequent Collaborators

4 joint publications

Henriëtte M G Willems

4 joint publications

John Skidmore

4 joint publications

Jonathan H Clarke

4 joint publications

Stephen P Andrews