John Skidmore
9PUBLICATIONS
28CO-AUTHORS
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Publications (9)
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|Nov 19, 2025
Development of Purine and Pyrrolopyrimidine Scaffolds as Potent, Selective, and Brain Penetrant NUAK1 Inhibitors.Gregory G Aldred, Helen K Boffey, Henriette M G Willems
|Feb 19, 2025
Development of the Pyrido[2,3-d]pyrimidin-7(8H)-one Scaffold toward Potent and Selective NUAK1 Inhibitors.Timothy P C Rooney, Gregory G Aldred, David Winpenny
|Sep 18, 2024
Inhibiting Ca2+ channels in Alzheimer's disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia.Nils Korte, Anna Barkaway, Jack Wells
|Aug 27, 2024
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents.Simon R Stockwell, Duncan E Scott, Gerhard Fischer
|Jan 04, 2024
p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.Lewis W Taylor, Elizabeth M Simzer, Claire Pimblett
|Oct 20, 2023
The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K).Gregory G Aldred, Timothy P C Rooney, Henriette M G Willems
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Frequent Collaborators
7 joint publications
Jonathan H Clarke
6 joint publications
Stephen P Andrews
5 joint publications
Timothy P C Rooney
5 joint publications
Henriëtte M G Willems
4 joint publications
Helen K Boffey
2 joint publications
Duncan E Scott
2 joint publications
Stephen J Chawner
2 joint publications
Christopher Green
1 joint publications
Gregory G Aldred
1 joint publications
Lewis W Taylor
