Timothy P C Rooney

7PUBLICATIONS
26CO-AUTHORS
Biologically active moleculesCheminformatics and quantitative structure-activity relationshipsMolecular targetsClinical pharmacology and therapeuticsProteins and peptides
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Publications (7)

|Sep 16, 2025
Tumour-specific STING agonist synthesis via a two-component prodrug system.

Nai-Shu Hsu, Cong Tang, Raquel V Mendes

|Feb 19, 2025
Development of the Pyrido[2,3-d]pyrimidin-7(8H)-one Scaffold toward Potent and Selective NUAK1 Inhibitors.

Timothy P C Rooney, Gregory G Aldred, David Winpenny

|Aug 27, 2024
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents.

Simon R Stockwell, Duncan E Scott, Gerhard Fischer

|Oct 20, 2023
The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K).

Gregory G Aldred, Timothy P C Rooney, Henriette M G Willems

|Dec 14, 2022
The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules.

Timothy P C Rooney, Gregory G Aldred, Helen K Boffey

|Feb 11, 2022
Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode.

Helen K Boffey, Timothy P C Rooney, Henriette M G Willems

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Frequent Collaborators

5 joint publications

John Skidmore

4 joint publications

Stephen P Andrews

4 joint publications

Jonathan H Clarke

3 joint publications

Henriëtte M G Willems