Florian Friedrich

7PUBLICATIONS
45CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiologically active moleculesEpigenetics (incl. genome methylation and epigenomics)Proteins and peptidesMolecular targets
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Publications (7)

|May 05, 2026
Development of High-Affinity CHD1 Chromodomain Inhibitors.

|Oct 30, 2025
From Pharmacophore to Warhead: NAD+-Targeting Triazoles as Mechanism-Based Sirtuin Inhibitors.

Florian Friedrich, Marat Meleshin, Niklas Papenkordt

|Sep 08, 2025
Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD+ co-factor binding.

Ricky Wirawan, Matthias Frei, Anna Heider

|Jul 10, 2025
Molecular determinants for recognition of serotonylated chromatin.

Laura Pulido-Cortés, Hajo Gielingh, Vito Thijssen

|May 20, 2025
Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions.

Florian Friedrich, Matthias Schiedel, Sören Swyter

|Jan 23, 2025
Structural Insights into Broad-Range Polyphosphate Kinase 2-II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis.

Marco Kuge, Michael Keppler, Florian Friedrich

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Frequent Collaborators

6 joint publications

Manfred Jung

4 joint publications

Oliver Einsle

3 joint publications

Wolfgang Sippl

3 joint publications

Niklas Papenkordt