Manfred Jung

65PUBLICATIONS
162CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiologically active moleculesMajor global burdens of diseaseGene and molecular therapyProteins and peptides
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Publications (65)

|May 05, 2026
Development of High-Affinity CHD1 Chromodomain Inhibitors.

|Oct 30, 2025
From Pharmacophore to Warhead: NAD<sup>+</sup>-Targeting Triazoles as Mechanism-Based Sirtuin Inhibitors.

Florian Friedrich, Marat Meleshin, Niklas Papenkordt

|Oct 07, 2025
Benzodeazaoxaflavin Sirtuin Inhibitors Inhibit <i>Schistosoma mansoni</i> Sirt2 and Cause Phenotypic Changes and Lethality in Schistosomula and Adult Worm Stages.

Roberto Gimmelli, Giuliana Papoff, Emanuele Fabbrizi

|Sep 08, 2025
Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD<sup>+</sup> co-factor binding.

Ricky Wirawan, Matthias Frei, Anna Heider

|Jun 17, 2025
Structure-Guided Design of a KMT9 Inhibitor Prodrug with Cellular Activity.

Sheng Wang, Nicolas P F Barthes, Sylvia Urban

|May 20, 2025
Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions.

Florian Friedrich, Matthias Schiedel, Sören Swyter

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Frequent Collaborators

20 joint publications

Wolfgang Sippl

8 joint publications

Christophe Romier

7 joint publications

Matthias Schiedel

7 joint publications

Niklas Papenkordt