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Christopher R Brown

5PUBLICATIONS

11CO-AUTHORS

Cheminformatics and quantitative structure-activity relationshipsGlycoconjugatesBiologically active molecules

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Publications (5)

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|Dec 10, 2024

High resistance barrier and prophylactic protection in preclinical models of SARS-CoV-2 with two siRNA combination.

Yesseinia I Anglero-Rodriguez, Florian A Lempp, Megha Subramanian

|Jun 23, 2022

From bench to bedside: Improving the clinical safety of GalNAc-siRNA conjugates using seed-pairing destabilization.

Mark K Schlegel, Maja M Janas, Yongfeng Jiang

|Oct 14, 2021

Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs.

Mark K Schlegel, Shigeo Matsuda, Christopher R Brown

|Sep 11, 2021

Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing.

Hartmut Jahns, Rohan Degaonkar, Peter Podbevsek

|Jul 16, 2021

Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo.

Hartmut Jahns, Nate Taneja, Jennifer L S Willoughby

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Frequent Collaborators

4 joint publications

Martin Egli

4 joint publications

Muthiah Manoharan

3 joint publications

Ivan Zlatev

3 joint publications

Vasant Jadhav

3 joint publications

Mark K Schlegel

2 joint publications

Martin A Maier

1 joint publications

Peter Podbevsek

1 joint publications

Swati Gupta

1 joint publications

Pawan Kumar

1 joint publications

Janez Plavec

Frequent Collaborators

4 joint publications

Martin Egli

4 joint publications

Muthiah Manoharan

3 joint publications

Ivan Zlatev

3 joint publications

Vasant Jadhav

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