Muthiah Manoharan

37PUBLICATIONS
37CO-AUTHORS
Biologically active moleculesFree radical chemistryCharacterisation of biological macromoleculesGlycoconjugatesReaction engineering (excl. nuclear reactions)
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Publications (37)

|Oct 23, 2026
Chiral-4'-Methyl-α-(l)-Threofuranosyl Nucleic Acids: Synthesis, Structure, Binding Affinity, Nuclease Resistance, and Polymerase Recognition.

|Jul 15, 2026
A Postsynthetic Strategy for Oligonucleotides Containing 2-Fluoro-adenine and Isoguanine Nucleobases.

|Apr 24, 2026
Synthesis and biophysical evaluation of C-5-triazolyl-functionalized morpholino-thymidine analogs.

|Apr 17, 2026
Acyclic serinol nucleic acid modification of siRNAs overcomes seed region mediated off-target effects while maintaining potency.

|Mar 23, 2026
Synthesis of siRNAs containing carbocyclic nucleotides and the role of cyclopentane conformation in RNAi activity.

Jayanta Kundu, Dhrubajyoti Datta, Masaaki Akabane-Nakata

|Dec 31, 2025
C‑Nucleosides Stabilize RNA by Reducing Nucleophilicity at 2'-OH.

Dipanwita Banerjee, Lu Xiao, Pavitra S Thacker

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Frequent Collaborators

29 joint publications

Martin Egli

10 joint publications

Mark K Schlegel

7 joint publications

Dhrubajyoti Datta

5 joint publications

Ivan Zlatev