Dhrubajyoti Datta

9PUBLICATIONS
11CO-AUTHORS
Free radical chemistryReaction engineering (excl. nuclear reactions)Functional materialsEnglish as a second languageBiomolecular modelling and design
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Publications (9)

|Jul 15, 2026
A Postsynthetic Strategy for Oligonucleotides Containing 2-Fluoro-adenine and Isoguanine Nucleobases.

|Mar 23, 2026
Synthesis of siRNAs containing carbocyclic nucleotides and the role of cyclopentane conformation in RNAi activity.

Jayanta Kundu, Dhrubajyoti Datta, Masaaki Akabane-Nakata

|Oct 23, 2025
Synthesis and Biophysical Properties of 3'-Deoxy-β-d-apio-d-furanosyl Nucleic Acids.

Victorio Jauregui-Matos, Dhrubajyoti Datta, Jayanta Kundu

|Apr 08, 2025
Expanding the binding space of argonaute-2: incorporation of either E or Z isomers of 6'-vinylphosphonate at the 5' end of the antisense strand improves RNAi activity.

Dhrubajyoti Datta, Jayanta Kundu, Patrick Miller

|Oct 21, 2024
Conformation matters: siRNAs with antisense strands with 5'-(E)-vinyl-phosphonate-α-L-LNA elicit stronger RNAi-mediated gene silencing than those with 5'-(E)-vinyl-phosphonate-LNA.

Dhrubajyoti Datta, Pawan Kumar, Soham Mandal

|May 05, 2023
Rational optimization of siRNA to ensure strand bias in the interaction with the RNA-induced silencing complex.

Dhrubajyoti Datta, Christopher S Theile, Kelly Wassarman

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Frequent Collaborators

6 joint publications

Martin Egli

6 joint publications

Muthiah Manoharan

2 joint publications

Jayanta Kundu

1 joint publications

Swagata Dasgupta