Patrick J Hrdlicka

10PUBLICATIONS
8CO-AUTHORS
Biologically active moleculesInstrumental methods (excl. immunological and bioassay methods)Micro-manipulationEnglish as a second languageCharacterisation of biological macromolecules
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Publications (10)

|Feb 12, 2026
DNA-targeting Invader probes: discovery, principles and applications.

Patrick J Hrdlicka, Michaela E Everly

|Oct 30, 2025
An electrophoretic mobility shift assay with chemiluminescent readout to evaluate DNA-targeting oligonucleotide-based probes.

Michaela E Everly, Peter J Wieber, Ibrahim Al Janabi

|Oct 20, 2025
Efficient and specific DNA-targeting using single-stranded LNA/MOE mixmers and chimeric Invader:XenoRNA probes.

Michaela E Everly, Patrick J Hrdlicka

|Oct 21, 2024
Conformation matters: siRNAs with antisense strands with 5'-(<i>E</i>)-vinyl-phosphonate-α-L-LNA elicit stronger RNAi-mediated gene silencing than those with 5'-(<i>E</i>)-vinyl-phosphonate-LNA.

Dhrubajyoti Datta, Pawan Kumar, Soham Mandal

|Oct 16, 2024
Recognition of mixed-sequence double-stranded DNA regions using chimeric Invader/LNA probes.

Michaela E Everly, Raymond G Emehiser, Patrick J Hrdlicka

|Oct 26, 2022
Serine-γPNA, Invader probes, and chimeras thereof: three probe chemistries that enable sequence-unrestricted recognition of double-stranded DNA.

Raymond G Emehiser, Karishma Dhuri, Caroline Shepard

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Frequent Collaborators

3 joint publications

Michaela E Everly

1 joint publications

Shiva P Adhikari

1 joint publications

Raman Bahal

1 joint publications

Dhrubajyoti Datta