Murray Coles

8PUBLICATIONS
31CO-AUTHORS
Molecular targetsHaematological tumoursProteins and peptidesBiomolecular modelling and designBiomaterials
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Publications (8)

|Dec 19, 2024
Covalent Fragments Acting as Tyrosine Mimics for Mutant p53-Y220C Rescue by Nucleophilic Aromatic Substitution.

Theresa Klett, Jason Stahlecker, Simon Jaag

|Dec 23, 2022
Revisiting a challenging p53 binding site: a diversity-optimized HEFLib reveals diverse binding modes in T-p53C-Y220C.

Jason Stahlecker, Theresa Klett, Martin Schwer

|Nov 18, 2022
A glutamine-based single α-helix scaffold to target globular proteins.

Albert Escobedo, Jonathan Piccirillo, Juan Aranda

|Oct 26, 2022
Screening of a Halogen-Enriched Fragment Library Leads to Unconventional Binding Modes.

Marcel Dammann, Jason Stahlecker, Markus O Zimmermann

|May 26, 2022
A topological refactoring design strategy yields highly stable granulopoietic proteins.

Julia Skokowa, Birte Hernandez Alvarez, Murray Coles

|Dec 22, 2020
Design of novel granulopoietic proteins by topological rescaffolding.

Birte Hernandez Alvarez, Julia Skokowa, Murray Coles

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