Charles A Lesburg

12PUBLICATIONS
82CO-AUTHORS
Biologically active moleculesChemical and thermal processes in energy and combustionProteins and peptidesChemical engineering designCheminformatics and quantitative structure-activity relationships
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Publications (12)

|May 14, 2025
The Discovery of Bridged Benzoazepine Amides as Selective Allosteric Modulators of RIPK1.

Joanna L Chen, Joey L Methot, Matthew J Mitcheltree

|Mar 25, 2022
Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.

Wonsuk Chang, Michael D Altman, Charles A Lesburg

|Mar 17, 2022
A kinase-cGAS cascade to synthesize a therapeutic STING activator.

John A McIntosh, Zhijian Liu, Brian M Andresen

|Mar 03, 2022
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Derun Li, David L Sloman, Abdelghani Achab

|Dec 30, 2021
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors.

Mitchell H Keylor, Anmol Gulati, Solomon D Kattar

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