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Xavier Fradera

12PUBLICATIONS
43CO-AUTHORS
Toxicology (incl. clinical toxicology)Molecular targetsBiologically active moleculesBiomolecular modelling and designProteins and peptides
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Journal

Publications (12)

Sort by Publication Date:
|Apr 29, 2026
Discovery of Potent and Selective Benzothiophene Difluoromethyl Phosphonate (DFMP) PTPN2/N1-Dual Inhibitors.

|Apr 22, 2022
Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.

Chunhui Huang, Christian Fischer, Michelle R Machacek

|Mar 03, 2022
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Derun Li, David L Sloman, Abdelghani Achab

|Feb 01, 2022
NMR Data-Driven Docking of HDM2-Inhibitor Complexes.

Xavier Fradera, Michael H Reutershan, Michelle R Machacek

|Oct 29, 2021
Discovery of <b>MK-4688</b>: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.

Michael H Reutershan, Michelle R Machacek, Michael D Altman

|Sep 17, 2021
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.

Brett Hopkins, Hongjun Zhang, Indu Bharathan

Pageof 2

Frequent Collaborators

3 joint publications

Charles A Lesburg

2 joint publications

Yongxin Han

2 joint publications

Mark McCoy

2 joint publications

Joey L Methot

2 joint publications

Theodore A Martinot

2 joint publications

David L Sloman

2 joint publications

Benjamin Wesley Trotter

2 joint publications

Michael H Reutershan

2 joint publications

Qinglin Pu

2 joint publications

Hongjun Zhang

Frequent Collaborators

3 joint publications

Charles A Lesburg

2 joint publications

Yongxin Han

2 joint publications

Mark McCoy

2 joint publications

Joey L Methot

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