David L Sloman

6PUBLICATIONS
30CO-AUTHORS
Proteins and peptidesMolecular targetsBiologically active molecules
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Publications (6)

|Apr 09, 2026
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design.

Xiaoshen Ma, David L Sloman, Timothy J Henderson

|Jun 26, 2024
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor.

Xiaoshen Ma, David L Sloman, Ruchia Duggal

|Apr 18, 2024
Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.

Esra Balıkçı, Anne-Sophie M C Marques, Ludwig G Bauer

|Apr 22, 2022
Diminishing GSH-Adduct Formation of Tricyclic Diazepine-based Mutant IDH1 Inhibitors.

Chunhui Huang, Christian Fischer, Michelle R Machacek

|Mar 03, 2022
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Derun Li, David L Sloman, Abdelghani Achab

|Nov 19, 2021
Comprehensive Strategies to Bicyclic Prolines: Applications in the Synthesis of Potent Arginase Inhibitors.

Derun Li, Hongjun Zhang, Thomas W Lyons

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