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Yongxin Han

6PUBLICATIONS

40CO-AUTHORS

Proteins and peptidesMolecular targetsCharacterisation of biological macromoleculesBiologically active moleculesChemical engineering design

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Publications (6)

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|Apr 09, 2026

From KRAS<sup><i>G12D</i></sup> to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design.

Xiaoshen Ma, David L Sloman, Timothy J Henderson

|Jun 26, 2024

Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS<sup>G12C</sup> Inhibitor.

Xiaoshen Ma, David L Sloman, Ruchia Duggal

|Apr 08, 2024

The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.

Meagan B Ryan, Bradley Quade, Natasha Schenk

|Aug 16, 2023

Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator.

Michael T Rudd, Peter J Manley, Barbara Hanney

|Mar 03, 2022

Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Derun Li, David L Sloman, Abdelghani Achab

|Sep 17, 2021

Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.

Brett Hopkins, Hongjun Zhang, Indu Bharathan

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Frequent Collaborators

3 joint publications

David L Sloman

2 joint publications

Hongjun Zhang

2 joint publications

Qinglin Pu

2 joint publications

Theodore A Martinot

2 joint publications

Xavier Fradera

2 joint publications

Charles A Lesburg

2 joint publications

David Jonathan Bennett

2 joint publications

Erik V Munsell

2 joint publications

Thomas W Lyons

2 joint publications

Xiaoshen Ma

Frequent Collaborators

3 joint publications

David L Sloman

2 joint publications

Hongjun Zhang

2 joint publications

Qinglin Pu

2 joint publications

Theodore A Martinot

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