Yongxin Han

7PUBLICATIONS
58CO-AUTHORS
Molecular targetsProteins and peptidesCharacterisation of biological macromoleculesBiologically active moleculesChemical engineering design
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Publications (7)

|Oct 23, 2026
Discovery of Novel Oral Covalent Inhibitors Targeting Active GTP-Bound KRASG12C with Potent Antitumor Activity.

|Apr 09, 2026
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design.

Xiaoshen Ma, David L Sloman, Timothy J Henderson

|Jun 26, 2024
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor.

Xiaoshen Ma, David L Sloman, Ruchia Duggal

|Apr 08, 2024
The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.

Meagan B Ryan, Bradley Quade, Natasha Schenk

|Aug 16, 2023
Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator.

Michael T Rudd, Peter J Manley, Barbara Hanney

|Mar 03, 2022
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Derun Li, David L Sloman, Abdelghani Achab

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Frequent Collaborators

3 joint publications

David Jonathan Bennett

3 joint publications

David L Sloman

3 joint publications

Erik V Munsell

2 joint publications

Hongjun Zhang