Yongxin Han

6PUBLICATIONS
40CO-AUTHORS
Proteins and peptidesMolecular targetsCharacterisation of biological macromoleculesBiologically active moleculesChemical engineering design
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Publications (6)

|Apr 09, 2026
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design.

Xiaoshen Ma, David L Sloman, Timothy J Henderson

|Jun 26, 2024
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor.

Xiaoshen Ma, David L Sloman, Ruchia Duggal

|Aug 16, 2023
Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator.

Michael T Rudd, Peter J Manley, Barbara Hanney

|Mar 03, 2022
Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing.

Derun Li, David L Sloman, Abdelghani Achab

|Sep 17, 2021
Utilization of Metabolite Identification and Structural Data to Guide Design of Low-Dose IDO1 Inhibitors.

Brett Hopkins, Hongjun Zhang, Indu Bharathan

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