David Jonathan Bennett

12PUBLICATIONS
114CO-AUTHORS
Molecular targetsToxicology (incl. clinical toxicology)Proteins and peptidesBiologically active moleculesChemical and thermal processes in energy and combustion
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Publications (12)

|Oct 23, 2026
Discovery of Novel Oral Covalent Inhibitors Targeting Active GTP-Bound KRASG12C with Potent Antitumor Activity.

|Apr 29, 2026
Discovery of Potent and Selective Benzothiophene Difluoromethyl Phosphonate (DFMP) PTPN2/N1-Dual Inhibitors.

|Apr 09, 2026
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design.

Xiaoshen Ma, David L Sloman, Timothy J Henderson

|Jun 26, 2024
Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor.

Xiaoshen Ma, David L Sloman, Ruchia Duggal

|Oct 20, 2023
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease.

Solomon D Kattar, Anmol Gulati, Kaila A Margrey

|Apr 04, 2023
General access to cubanes as benzene bioisosteres.

Mario P Wiesenfeldt, James A Rossi-Ashton, Ian B Perry

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Frequent Collaborators

3 joint publications

Thomas W Lyons

3 joint publications

Ellen C Minnihan

3 joint publications

Erik V Munsell

3 joint publications

Charles A Lesburg