Xu Wang

7PUBLICATIONS
29CO-AUTHORS
Infectious agentsBiomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsMedical parasitologyVeterinary bacteriology
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (7)

|Mar 12, 2026
Structure-Activity Relationships among Inhibitors of Acinetobacter baumannii and Klebsiella pneumoniae 1-Deoxy-d-xylulose 5-Phosphate Reductoisomerase (DXR/IspC) - A Promising Target for Antibiotic Development.

Misgina Girma, Meagan Belcher Dufrisne, Archi Sehgal

|Jun 03, 2025
Metabolic Activation versus Masked Prodrugs: Bisubstrate Mimic Inhibitors of CoaBC's PPCS Activity in Mycobacterium tuberculosis and Staphylococcus aureus.

Timothy J Kotzé, Konrad J Mostert, Riyad Domingo

|Nov 08, 2024
Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer.

Dimitar Gotchev, Shuai Chen, Benjamin Dugan

|Oct 25, 2024
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.

Xu Wang, Dimitar Gotchev, Kristi Yi Fan

|Jun 13, 2023
MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase.

Xu Wang, Rachel L Edwards, Haley S Ball

|Nov 01, 2021
Mechanism of Action of N-Acyl and N-Alkoxy Fosmidomycin Analogs: Mono- and Bisubstrate Inhibition of IspC from Plasmodium falciparum, a Causative Agent of Malaria.

Misgina B Girma, Haley S Ball, Xu Wang

Pageof 2

Frequent Collaborators

2 joint publications

Angela M Lam

2 joint publications

Audrey R Odom John

2 joint publications

Dimitar Gotchev

2 joint publications

Cynthia S Dowd