Angela M Lam

6PUBLICATIONS
14CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMedical molecular engineering of nucleic acids and proteinsBiologically active molecules
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (6)

|Nov 08, 2024
Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer.

Dimitar Gotchev, Shuai Chen, Benjamin Dugan

|Oct 25, 2024
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.

Xu Wang, Dimitar Gotchev, Kristi Yi Fan

|Sep 22, 2024
Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA Therapeutic.

Emily P Thi, Xin Ye, Nicholas M Snead

|Sep 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators.

Eugen F Mesaros, Andrew G Cole, Steven G Kultgen

|Apr 23, 2024
Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2.

Eugen F Mesaros, Benjamin J Dugan, Min Gao

|Mar 28, 2024
Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161.

Angela M Lam, Ravi R Dugyala, Muhammed Sheraz

Pageof 1

Frequent Collaborators

4 joint publications

Ingrid Graves

3 joint publications

Andrew G Cole

3 joint publications

Emily P Thi

2 joint publications

Jeremy D Mason