Ingrid Graves

5PUBLICATIONS
14CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMedical molecular engineering of nucleic acids and proteinsBiomolecular modelling and designBiologically active molecules
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (5)

|Nov 08, 2024
Structure-Activity Relationships and Discovery of (<i>S</i>)-5-(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-<i>h</i>]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer.

Dimitar Gotchev, Shuai Chen, Benjamin Dugan

|Sep 22, 2024
Control of Hepatitis B Virus with Imdusiran, a Small Interfering RNA Therapeutic.

Emily P Thi, Xin Ye, Nicholas M Snead

|Sep 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators.

Eugen F Mesaros, Andrew G Cole, Steven G Kultgen

|Sep 04, 2024
Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836.

Andrew G Cole, Steven G Kultgen, Nagraj Mani

|Mar 28, 2024
Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161.

Angela M Lam, Ravi R Dugyala, Muhammed Sheraz

Pageof 1

Frequent Collaborators

4 joint publications

Angela M Lam

4 joint publications

Emily P Thi

3 joint publications

Andrew G Cole

2 joint publications

Jeremy D Mason