Dimitar Gotchev

3PUBLICATIONS
12CO-AUTHORS
Cheminformatics and quantitative structure-activity relationships
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Publications (3)

|Nov 08, 2024
Structure-Activity Relationships and Discovery of (S)-5-(tert-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-h]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer.

Dimitar Gotchev, Shuai Chen, Benjamin Dugan

|Oct 25, 2024
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.

Xu Wang, Dimitar Gotchev, Kristi Yi Fan

|Jan 08, 2024
Structure-Activity Relationships and Discovery of (S)-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6H-pyrido[1,2-h][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer.

Dimitar Gotchev, Bruce D Dorsey, Duyan Nguyen

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Frequent Collaborators

2 joint publications

Xu Wang

2 joint publications

Angela M Lam

1 joint publications

Laurèn Bailey

1 joint publications

Amy C-H Lee