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Dimitar Gotchev

3PUBLICATIONS

12CO-AUTHORS

Cheminformatics and quantitative structure-activity relationships

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Publications (3)

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|Nov 08, 2024

Structure-Activity Relationships and Discovery of (<i>S</i>)-5-(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2',1':2,3]imidazo[4,5-<i>h</i>]quinoline-3-carboxylic Acid (AB-161), a Novel Orally Available and Liver-Centric HBV RNA Destabilizer.

Dimitar Gotchev, Shuai Chen, Benjamin Dugan

|Oct 25, 2024

Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 M<sup>pro</sup> from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.

Xu Wang, Dimitar Gotchev, Kristi Yi Fan

|Jan 08, 2024

Structure-Activity Relationships and Discovery of (<i>S</i>)-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6<i>H</i>-pyrido[1,2-<i>h</i>][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer.

Dimitar Gotchev, Bruce D Dorsey, Duyan Nguyen

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Frequent Collaborators

2 joint publications

Xu Wang

2 joint publications

Angela M Lam

1 joint publications

Laurèn Bailey

1 joint publications

Amy C-H Lee

1 joint publications

Kristi Yi Fan

1 joint publications

Marvin M Vega

1 joint publications

Matthew A Clark

1 joint publications

Andrew G Cole

1 joint publications

Michael J Sofia

1 joint publications

Ingrid E Graves

Frequent Collaborators

2 joint publications

Xu Wang

2 joint publications

Angela M Lam

1 joint publications

Laurèn Bailey

1 joint publications

Amy C-H Lee

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