Andrew G Cole

5PUBLICATIONS
16CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designBiologically active molecules
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Publications (5)

|Oct 25, 2024
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.

Xu Wang, Dimitar Gotchev, Kristi Yi Fan

|Sep 18, 2024
Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators.

Eugen F Mesaros, Andrew G Cole, Steven G Kultgen

|Sep 04, 2024
Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836.

Andrew G Cole, Steven G Kultgen, Nagraj Mani

|Mar 28, 2024
Preclinical Antiviral and Safety Profiling of the HBV RNA Destabilizer AB-161.

Angela M Lam, Ravi R Dugyala, Muhammed Sheraz

|Apr 18, 2022
The identification of highly efficacious functionalised tetrahydrocyclopenta[c]pyrroles as inhibitors of HBV viral replication through modulation of HBV capsid assembly.

Andrew G Cole, Steven G Kultgen, Nagraj Mani

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Frequent Collaborators

3 joint publications

Emily P Thi

3 joint publications

Angela M Lam

3 joint publications

Ingrid Graves

3 joint publications

Kristi Yi Fan