Brian Safina

4PUBLICATIONS
8CO-AUTHORS
Computational physiologyCheminformatics and quantitative structure-activity relationshipsMolecular targets
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Publications (4)

|Mar 22, 2021
Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy.

Jack A Terrett, Huifen Chen, Daniel G Shore

|Dec 01, 2018
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (NaV) 1.7 with Potent Analgesic Activity.

Shaoyi Sun, Qi Jia, Alla Y Zenova

|May 09, 2018
Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain.

Thilo Focken, Sultan Chowdhury, Alla Zenova

|Dec 12, 2017
Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity.

BinQing Wei, Janet Gunzner-Toste, Hui Yao

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Frequent Collaborators

2 joint publications

Thilo Focken

1 joint publications

Benjamin D Sellers

1 joint publications

Christoph M Dehnhardt

1 joint publications

Jack A Terrett