Philippe N Bolduc

11PUBLICATIONS
47CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Biomolecular modelling and designPharmaceutical delivery technologiesCheminformatics and quantitative structure-activity relationshipsInnate immunity
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Publications (11)

|Mar 17, 2026
Discovery and Optimization of Thienopyrazine RNA-Splicing Modulators for the Treatment of Huntington's Disease.

Chaofan Xu, Neeta Abraham, Nupur Bansal

|Nov 11, 2025
Triply convergent Ni-electrocatalytic assembly of 1,1-diaryl cyclobutanes, azetidines and oxetanes.

Luca Massaro, Philipp Neigenfind, Andrew Feng

|May 07, 2025
PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry.

Brendon E Cook, Thomas C Pickel, Sangram Nag

|May 15, 2024
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.

Philippe N Bolduc, Magnus Pfaffenbach, Ryan Evans

|May 02, 2024
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.

Magnus Pfaffenbach, Philippe N Bolduc, Zhili Xin

|Apr 04, 2024
Carbon quaternization of redox active esters and olefins by decarboxylative coupling.

Xu-Cheng Gan, Benxiang Zhang, Nathan Dao

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