Magnus Pfaffenbach

5PUBLICATIONS
4CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Cheminformatics and quantitative structure-activity relationshipsInnate immunityBiologically active moleculesProteins and peptides
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Publications (5)

|Mar 17, 2026
Discovery and Optimization of Thienopyrazine RNA-Splicing Modulators for the Treatment of Huntington's Disease.

Chaofan Xu, Neeta Abraham, Nupur Bansal

|May 15, 2024
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.

Philippe N Bolduc, Magnus Pfaffenbach, Ryan Evans

|May 02, 2024
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.

Magnus Pfaffenbach, Philippe N Bolduc, Zhili Xin

|Mar 12, 2024
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke.

Ryan Evans, Philippe N Bolduc, Magnus Pfaffenbach

|Aug 12, 2022
Synthesis of N-Substituted 3-Amino-2-pyridones.

Philippe N Bolduc, Magnus Pfaffenbach, Vanna D Blasczak

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Frequent Collaborators

5 joint publications

Philippe N Bolduc

5 joint publications

Emily A Peterson

3 joint publications

Pei Li

1 joint publications

Brian T Hopkins