Pei Li

5PUBLICATIONS
4CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsInnate immunityBiologically active moleculesQuality assurance, chemometrics, traceability and metrological chemistryBioassays
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Journal

Publications (5)

|May 15, 2024
A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.

Philippe N Bolduc, Magnus Pfaffenbach, Ryan Evans

|May 02, 2024
Discovery of BIO-8169─A Highly Potent, Selective, and Brain-Penetrant IRAK4 Inhibitor for the Treatment of Neuroinflammation.

Magnus Pfaffenbach, Philippe N Bolduc, Zhili Xin

|Mar 12, 2024
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke.

Ryan Evans, Philippe N Bolduc, Magnus Pfaffenbach

|Nov 17, 2020
Perspectives on updates, clarifications and controversies in chromatographic assay guidance for bioanalytical method validation from major regulatory agencies and organizations.

Kris King, Pei Li, Alicia Pietrasiewicz

|Jul 07, 2020
Hybridization Liquid Chromatography-Tandem Mass Spectrometry: An Alternative Bioanalytical Method for Antisense Oligonucleotide Quantitation in Plasma and Tissue Samples.

Pei Li, Yuqing Gong, Jaeah Kim

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Frequent Collaborators

3 joint publications

Philippe N Bolduc

3 joint publications

Magnus Pfaffenbach

3 joint publications

Emily A Peterson

1 joint publications

Brian T Hopkins