Xiaojiang S Chen

21PUBLICATIONS
46CO-AUTHORS
Haematological tumoursMedical devicesMolecular targetsSensory systemsBiological network analysis
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (21)

|Apr 19, 2025
Structural basis for Polθ-helicase DNA binding and microhomology-mediated end-joining.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Oct 10, 2024
Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain.

Hanjing Yang, Josue Pacheco, Kyumin Kim

|Aug 14, 2024
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Jun 19, 2024
Structural Basis for Polθ-Helicase DNA Binding and Microhomology-Mediated End-Joining.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Apr 13, 2024
Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15.

Fumiaki Ito, Hanjing Yang, Z Hong Zhou

|Apr 05, 2024
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.

William Fried, Mrityunjay Tyagi, Leonid Minakhin

Pageof 4