Neil Johnson

6PUBLICATIONS
40CO-AUTHORS
Molecular targetsCancer therapy (excl. chemotherapy and radiation therapy)Mechanobiology
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Publications (6)

|Aug 14, 2024
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Jul 09, 2024
FAM122A ensures cell cycle interphase progression and checkpoint control by inhibiting B55α/PP2A through helical motifs.

Jason S Wasserman, Bulat Faezov, Kishan R Patel

|Apr 05, 2024
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.

William Fried, Mrityunjay Tyagi, Leonid Minakhin

|Dec 08, 2023
4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress.

Marissa L Calbert, Gurushankar Chandramouly, Clare M Adams

|Nov 24, 2023
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities.

John J Krais, David J Glass, Ilse Chudoba

|Aug 19, 2021
RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage.

John J Krais, Yifan Wang, Pooja Patel

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