Richard T Pomerantz

13PUBLICATIONS
47CO-AUTHORS
Haematological tumoursBiologically active moleculesMolecular targetsPreventative health careCancer therapy (excl. chemotherapy and radiation therapy)
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Publications (13)

|Apr 19, 2025
Structural basis for Polθ-helicase DNA binding and microhomology-mediated end-joining.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Oct 17, 2024
Template-Independent Enzymatic RNA Synthesis.

Nilesh B Karalkar, Tatiana Kent, Taylor Tredinnick

|Aug 14, 2024
Structural basis for a Polθ helicase small-molecule inhibitor revealed by cryo-EM.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Jul 10, 2024
PARG is essential for Polθ-mediated DNA end-joining by removing repressive poly-ADP-ribose marks.

Umeshkumar Vekariya, Leonid Minakhin, Gurushankar Chandramouly

|Jun 19, 2024
Structural Basis for Polθ-Helicase DNA Binding and Microhomology-Mediated End-Joining.

Fumiaki Ito, Ziyuan Li, Leonid Minakhin

|Apr 05, 2024
Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors.

William Fried, Mrityunjay Tyagi, Leonid Minakhin

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