Roberta Cascella

21PUBLICATIONS
54CO-AUTHORS
Industrial molecular engineering of nucleic acids and proteinsNeurology and neuromuscular diseasesProteins and peptidesMolecular targetsCentral nervous system
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Publications (21)

|Mar 28, 2026
Engineering a dimeric single-domain antibody for improved detection and neutralization of amyloid-β oligomers.

Liliana Napolitano, Devkee M Vadukul, Alessandra Bigi

|Dec 09, 2025
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates.

Alessandra Bigi, Andrea Carlotta Conti, Liliana Napolitano

|Apr 03, 2024
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates.

Serene W Chen, Joseph D Barritt, Roberta Cascella

|Jul 11, 2023
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes.

Silvia Errico, Giacomo Lucchesi, Davide Odino

|May 13, 2023
The Toxicity of Protein Aggregates: New Insights into the Mechanisms.

Alessandra Bigi, Eva Lombardo, Roberta Cascella

|Apr 18, 2023
Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases.

Ryan Limbocker, Nunilo Cremades, Roberta Cascella

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Frequent Collaborators

17 joint publications

Cristina Cecchi

13 joint publications

Alessandra Bigi

10 joint publications

Fabrizio Chiti

5 joint publications

Nunilo Cremades