Alessandra Bigi

18PUBLICATIONS
46CO-AUTHORS
Proteomics and intermolecular interactions (excl. medical proteomics)Cellular nervous systemIndustrial molecular engineering of nucleic acids and proteinsNeurology and neuromuscular diseasesMicrobial taxonomy
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Publications (18)

|Aug 13, 2026
Structure-Activity Relationship Study of Protoberberine Alkaloids Reveals Molecular Planarity as a Key Determinant of Membrane Interaction and Protection from Misfolded Protein Oligomers.

|May 02, 2026
Unraveling in vitro phase separation and aggregation properties of the structured region of FMRP and the impact of Fragile X syndrome-linked mutations.

|Mar 28, 2026
Engineering a dimeric single-domain antibody for improved detection and neutralization of amyloid-β oligomers.

Liliana Napolitano, Devkee M Vadukul, Alessandra Bigi

|Dec 09, 2025
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates.

Alessandra Bigi, Andrea Carlotta Conti, Liliana Napolitano

|Sep 21, 2025
Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer's disease.

Sara Sepe, Federica Rey, Alexandra Mancheno-Ferris

|Apr 03, 2024
Structure-Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates.

Serene W Chen, Joseph D Barritt, Roberta Cascella

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Frequent Collaborators

15 joint publications

Cristina Cecchi

13 joint publications

Roberta Cascella

11 joint publications

Fabrizio Chiti

3 joint publications

Nunilo Cremades